Most tooth and mouth pain is best managed by over the counter, anti-inflammatory medications like ibuprofen (i.e. Advil or Motrin). Pain can often be managed with as little as 200-400mg of ibuprofen up to four times per day. If pain persists, 500mg of acetominophen (i.e. Tylenol) can be added to the ibuprofen. In extreme cases, a narcotic like Tylenol 3 may need to be prescribed.